Comparison of corticosteroid and sulphasalazine therapy in ulcerative colitis.
نویسندگان
چکیده
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منابع مشابه
Evaluation of low doses of Azathioprine in reducing relapse and corticosteroid dependence in patients with Ulcerative Colitis
Background and Aim: Ulcerative Colitis is an idiopathic inflammatory bowel disease that is common in adults. Although corticosteroids are the most effective preservative treatment for Ulcerative Colitis. However, due to the dependence of these drugs and their serious complications, the use of an immunosuppressive drug or surgery should be taken seriously. Thus the aim of the study was the evalu...
متن کاملControlled Trial of Sulphasalazine in the Treatment of Ulcerative Colitis.
EDITORIAL SYNOPSIS This paper provides further evidence that sulphasalazine is an effective agent in the treatment of mild or moderate colitis. There was a high incidence of gastrointestinal side-effects and one patient developed haemolytic anaemia. Sulphasalazine (salicylazosulphapyridine, Salazo-pyrin, Asulfidine) was first used by Svartz (1942) in the treatment of rheumatoid arthritis. Later...
متن کاملControlled therapeutic trial of levamisole and sulphasalazine in acute ulcerative colitis.
Forty five patients with acute ulcerative colitis were randomly allocated to receive (a) sulphasalazine, (b) levamisole, or (c) a combination of sulphasalazine and levamisole. Each group contained 15 patients. The ulcerative colitis activity index (UCAI), the remission and relapse rates were compared at three monthly intervals for one year. The UCAI fell in each group. Detailed analysis of all ...
متن کاملRed cell abnormalities associated with sulphasalazine maintenance therapy for ulcerative colitis.
Of 52 patients receiving a mean dose of 2.5g sulphasalazine/day as maintenance therapy for ulcerative colitis, 35 were found to have one or more drug-induced red cell abnormalities, which were not found in 50 normal controls or in 10 colitics not receiving sulphasalazine. Twenty-three of the treated patients had contracted red cells, an abnormality that is thought to result in mild haemolysis. ...
متن کاملRaised serum alkaline phosphatase and aspartate transaminase levels in two rheumatoid patients treated with sulphasalazine.
Hepatotoxicity is a rare complication of sulphasalazine therapy in ulcerative colitis. This report describes two rheumatoid patients in whom raised serum levels of liver enzymes occurred soon after starting sulphasalazine treatment for their arthritis. In both cases the serum enzyme levels returned to normal after stopping the drug. Drug-induced hepatotoxicity should be considered in patients w...
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Background and Objectives: Ulcerative Colitis is an inflammation of colon mucosa that is treated by corticosteroids. Our aim in this study was to report a case of immunodeficiency in this disease caused by long-term corticosteroid treatment. Case Report: This study was a case report of ulcerative colitis patient, who has been using prednisolone from five years ago till now without the doctor's...
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ورودعنوان ژورنال:
- British medical journal
دوره 2 5321 شماره
صفحات -
تاریخ انتشار 1962